Fibroblast Banking
What Are Fibroblasts?
Fibroblasts are important cells found in living organisms that serve as the predominant cell type in connective tissue. They are responsible for producing the proteins that form the structure of connective tissue and for contributing to its repair. Additionally, fibroblasts play a significant role in wound healing and tissue regeneration processes.
Their primary responsibility is the production of proteins that form the extracellular matrix, which provides structural support to the body’s organs. Key structural proteins such as collagen, elastin, and fibronectin are among the substances synthesized by fibroblasts, ensuring the strength, flexibility, and durability of tissues.
What Is Fibrogel?
These are custom-made fillers developed using tissue engineering technology and used for the first time in regenerative medicine. Autologous fibroblast cell cultures are combined with the patient’s plasma, which has been converted into a gel form; they are used both as a filler and as an anti-aging treatment method that boosts collagen production.
Fibrogel is the first and only filler method made using the patient’s own fibroblast cells. As a “youth vaccine” filler, Fibrogel offers superior results and longevity compared to other medical and cosmetic applications due to the body’s recognition of its own cells, effectively eliminating skin wrinkles through its rejuvenating and volumizing effects.
Applications
Elimination of facial wrinkles,
Lip augmentation,
Treatment of depressions caused by burns, previous surgery, or trauma,
Facial rejuvenation procedures performed with mesotherapy,
Correction of deformities resulting from acne or chickenpox,
Treatment of chronic non-healing wounds
Treatment of long-term skin scars
Advantages Over Other Treatments
Hypoallergenic: Since the body recognizes Fibrogel during injections, it does not trigger an immune response to foreign substances. Therefore, there is absolutely no risk of an allergic reaction compared to fillers made from synthetic sources such as HA.
No risk of transmitting animal-borne diseases: Since autologous (personal) tissue is used in the Fibrogel procedure, serum derived from the patient’s own blood is used during the cell development and proliferation stages instead of commercially available serum from animal sources. Therefore, there is absolutely no risk of transmitting animal-borne diseases.
It is long-lasting and has sustained effects: With this method, live autologous fibroblasts, which have been multiplied in number, are injected directly into the targeted area in the patient, where they establish a continuous collagen repair system. Recent findings indicate measurable improvement lasting from at least 12 months up to 48 months. Histological analyses in these studies confirm that fibroblast injection promotes collagen production and, consequently, increases the density of dermal collagen.
Tissue Harvesting Procedure
The treatment area is first anesthetized locally and topically. A biopsy is then performed to obtain a tissue sample of approximately 2×4 mm from behind the ear or behind the earlobe. Since punch biopsies are likely to leave a scar, an excisional biopsy is recommended.
Freezing for Future Use
As part of Genkord’s cell banking services, we offer a storage service to preserve patients’ cells for future use, upon their request. To ensure that the cultured cells remain intact for many years, they are stored in liquid nitrogen tanks at -196°C with the addition of special solutions. On the day of use, they are thawed and prepared for the procedure.